Membrane cartridges

UltraPure Plus

Nylon 6,6 membrane cartridge

Microbial control and clarification in industrial, pharmaceutical, and water processes

Nylon 6,6 membrane cartridge, from 0.1 to 1.2 µm and steam-sterilizable, for water treatment, beverages, and pharmaceutical and biological solutions.

Line: UltraPure · Nylon 6,6
Pore sizes: 0.1 µm to 1.2 µm
Lengths: 10″ · 20″ · 30″ · 40″
Manufacturing: Argentina · ISO 7 cleanroom

Request a quote

UltraPure Plus, nylon 6,6 membrane cartridge by Exova

Description

The UltraPure Plus is a nylon 6,6 membrane filter cartridge for microorganism control and fluid clarification in industrial processes. It works as a final filter or as upstream protection for final filters.

Its uses range from water treatment and beverages to parenteral solutions, ophthalmics, sera and blood products, biological products, veterinary pharmaceutical solutions, and culture media.

The membrane is naturally hydrophilic: it filters with high flow rates and a very low pressure drop. The 0.1 and 0.2 µm ratings retain more than 10⁷ Brevundimonas diminuta per cm², according to the FDA definition of sterilizing-grade filters; the 0.1 µm rating also retains more than 10⁴ Acholeplasma laidlawii per cm².

It withstands repeated steam sterilizations, in-line or in an autoclave, and sanitization with hot water at 80 °C and chemical cleaning and disinfection agents, so it can be reused. It is manufactured in an ISO 7 cleanroom.

Hydrophilic nylon 6,6 membrane

Naturally hydrophilic: high flow rates and a very low pressure drop, as a final filter or as upstream protection.

Declared retention by rating

0.1 and 0.2 µm: more than 10⁷/cm² of Brevundimonas diminuta. 0.45 µm: Serratia marcescens. 0.65 µm: Saccharomyces cerevisiae.

Pharmaceutical and water uses

Parenteral solutions, ophthalmics, sera and blood products, biological products, culture media, and water treatment.

Sterilizable and reusable

Multiple cycles of 30 to 60 minutes with steam at 121 °C, in-line or in an autoclave, and with hot water at 80 °C.

Chemical sanitization

Peracetic acid up to 1 % (10,000 ppm) at room temperature and sodium hydroxide up to 1 %, in cycles of 30 to 60 minutes.

FDA 21 CFR 177 and ISO 7 cleanroom

Materials compliant with FDA 21 CFR 177 and Directive 2002/72/EC for food contact, and manufactured in an ISO 7 cleanroom.

Microbial retention

Values stated in the UltraPure Plus catalog.

0.1 µm > 10⁴/cm² Acholeplasma laidlawii

0.1 and 0.2 µm > 10⁷/cm² Brevundimonas diminuta According to the FDA definition of sterilizing-grade filters

0.45 µm > 10⁷/cm² Serratia marcescens

0.65 µm > 10⁷/cm² Saccharomyces cerevisiae

Technical specifications

Request the PDF catalog

Materials

Filter medium	Nylon 6,6
Outer and inner support layers	Polypropylene
Outer cage and core	Polypropylene
Flat ends and fin	Polypropylene
Adapter (222 and 226)	Polypropylene with internal reinforcement
O-rings	Silicone, Viton, Buna, EPDM, PTFE-encapsulated Viton

Dimensions

Nominal filtration area	8,000 cm² per 10″
Nominal length	10″ (254 mm), 20″ (508 mm), 30″ (762 mm), and 40″ (1,016 mm)
Nominal diameter	2.75″ (70 mm)

Operating conditions

Maximum differential pressure	5.5 bar (80 psi) at 25 °C
Maximum differential pressure in reverse flow	0.69 bar (10 psi) at 25 °C
Maximum differential pressure for change-out	2 bar

Sterilization and sanitization

Steam sterilization	Multiple cycles of 30 to 60 minutes at 121 °C, in-line or in an autoclave (1)
Hot water sanitization	Multiple cycles of 30 to 60 minutes at 80 °C (1)
Chemical sanitization	Multiple cycles of 30 to 60 minutes with peracetic acid up to 1 % (10,000 ppm), at room temperature
Chemical cleaning	Multiple cycles of 30 to 60 minutes with sodium hydroxide up to 1 % (10,000 ppm) (1)
Note (1)	Recommended only for single-open-end cartridges with internal reinforcement at the 226 / 222 O-ring fitting

Quality and compliance

Materials compliant with FDA 21 CFR 177 for food contact
Complies with European Commission Directive 2002/72/EC on plastic materials in contact with food, with its amendments up to 2008/39/EC
Manufactured in an ISO 7 cleanroom

Applications

Water treatment
Culture media
Veterinary pharmaceutical solutions
Biological products
Prefiltration ahead of final filters
Parenteral solutions
Sera and blood products
Beverages
Ophthalmics

Industries

Pharmaceutical and biotech Water treatment Food and beverage SaniFlow filter housings

Frequently asked questions

Which processes is it used in?

In water treatment, beverages, parenteral solutions, ophthalmics, sera and blood products, biological products, veterinary pharmaceutical solutions, and culture media, as a final filter or as a prefilter ahead of final filters.

Can it be used as a sterilizing filter?

The 0.1 and 0.2 µm ratings retain more than 10⁷ Brevundimonas diminuta per cm², according to the FDA definition of sterilizing-grade filters. The 0.1 µm rating also retains more than 10⁴ Acholeplasma laidlawii per cm².

Can it be steam-sterilized in place?

Yes. It withstands multiple cycles of 30 to 60 minutes at 121 °C, with in-line steam or in an autoclave, and the cartridge can be reused. It is recommended only for single-open-end cartridges with internal reinforcement at the 226 or 222 O-ring fitting.

Which chemicals can be used for sanitizing and cleaning?

Peracetic acid up to 1 % (10,000 ppm) at room temperature for sanitizing, and sodium hydroxide up to 1 % (10,000 ppm) for cleaning, in multiple cycles of 30 to 60 minutes.

What lengths and connections are available?

A 2.75″ (70 mm) diameter and lengths of 10″, 20″, 30″, and 40″. It is offered with double 226 or 222 O-rings, with a fin or a flat end, or as double open end (DOE).

UltraPure line