Prefiltration

PreFiber A PP + PES

Absolute-rated dual-layer PP + PES cartridge

Absolute prefiltration and bioburden reduction ahead of the final membrane filter

Pleated polypropylene and PES membrane cartridge, absolute pore size 0.1 to 1.2 µm. Protects final filters in biopharma and in wine, beer, and bottled water.

Line: PreFiber · Depth medium (polypropylene or glass microfiber) + PES membrane
Ratings: 0.1 µm to 1.2 µm
Lengths: 10″ · 20″ · 30″ · 40″
Manufacturing: Argentina · ISO 7 cleanroom

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PreFiber A PP + PES, absolute-rated dual-layer PP + PES cartridge by Exova

Description

The PreFiber A PP + PES is a dual-layer hybrid filter cartridge: a pleated polypropylene depth medium followed by a polyethersulfone (PES) membrane as the final filter, in a single element. It is used as a prefilter for final membrane filter cartridges, to reduce the bioburden reaching them and extend their service life.

Its ratings are specified as absolute, from 0.1 to 1.2 µm, and the prefilter pore size, from 0.5 to 3 µm, is also stated for each one. It offers 6,700 cm² of filtration area per 10″.

It is suitable for protein solutions, sera, vaccines, and culture media, as well as for wine, beer, and bottled water. It withstands steam sterilization at 121 °C and sanitization with hot water at 80 °C and with chemicals, which allows it to be reused. It is manufactured in an ISO 7 cleanroom.

Absolute rating from 0.1 to 1.2 µm

Six ratings (0.1, 0.2, 0.4, 0.6, 0.8, and 1.2 µm), each with its prefilter pore size stated.

Polypropylene + PES membrane

Pleated depth medium upstream and a polyethersulfone membrane as the final filter, in the same cartridge.

6,700 cm² per 10″

Nominal filtration area, in lengths of 10″, 20″, 30″, and 40″.

Steam at 121 °C and water at 80 °C

Multiple cycles of 30 to 60 minutes in single-open-end cartridges.

Biopharma and beverages

Sera, vaccines, culture media, and protein solutions; also wine, beer, and bottled water.

Manufactured in an ISO 7 cleanroom

Materials compliant with FDA 21 CFR 177 for food contact and non-toxic components according to the Argentine Food Code.

Technical specifications

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Materials

Upstream filter medium	Pleated polypropylene depth medium
Downstream filter medium (final filter)	Polyethersulfone (PES) membrane
Outer and inner support layers	Polypropylene
Outer cage, core, and flat ends	Polypropylene
Fin	Polypropylene
Adapter (222 and 226)	Polypropylene with internal reinforcement
O-rings	Silicone, Viton®, Buna, EPDM, Teflon®-encapsulated Viton®

Dimensions

Nominal filtration area	6,700 cm² per 10″
Nominal length	10″ (254 mm), 20″ (508 mm), 30″ (762 mm), and 40″ (1,016 mm)
Nominal diameter	2.75″

Operating conditions

Maximum differential pressure	5.5 bar (80 psi) at 25 °C
Maximum differential pressure in reverse flow	0.69 bar (10 psi) at 25 °C
Change-out differential pressure	2 bar

Sterilization and sanitization

Steam sterilization	Multiple cycles of 30 to 60 minutes at 121 °C, in-line or in an autoclave (1)
Hot water sanitization	Multiple cycles of 30 to 60 minutes at 80 °C (1)
Chemical sanitization	Multiple cycles of 30 to 60 minutes with peracetic acid or sodium hydroxide up to 1 % (10,000 ppm)
Note (1)	Suitable only for single-open-end cartridges

Quality and compliance

Materials compliant with FDA 21 CFR 177 for food contact
Complies with European Commission Directive 2002/72/EC on plastic materials in contact with food, with its amendments up to 2008/39/EC
Non-toxic components according to the migration test of the Argentine Food Code and Mercosur SGT3 standards
Manufactured in an ISO 7 cleanroom

Selection data

Available pore sizes (absolute)
Final pore size	Prefilter pore size
0.1 µm	0.5 µm
0.2 µm	0.7 µm
0.4 µm	1 µm
0.6 µm	2 µm
0.8 µm	2 µm
1.2 µm	3 µm

Applications

Protein solutions
Sera
Vaccines
Culture media
Protection of final membrane cartridges
Wine
Beer
Bottled water

Industries

Pharmaceutical and biotech Food and beverage Wine industry SaniFlow filter housings

Frequently asked questions

What ratings does the PreFiber A PP + PES come in?

Six absolute final-filter ratings: 0.1, 0.2, 0.4, 0.6, 0.8, and 1.2 µm. The prefilter for each rating ranges from 0.5 µm (in the 0.1 µm rating) to 3 µm (in the 1.2 µm rating).

Can it be used for wine, beer, or bottled water?

Yes. They are among its applications, and its materials are compliant with FDA 21 CFR 177 for food contact and comply with the migration test of the Argentine Food Code and Mercosur SGT3 standards.

Which configurations support steam and hot water?

Steam sterilization at 121 °C and water sanitization at 80 °C are suitable only for single-open-end cartridges.

What differential pressure can it withstand?

5.5 bar (80 psi) at 25 °C in normal flow and 0.69 bar (10 psi) at 25 °C in reverse flow. The change-out differential pressure is 2 bar.

How does it differ from the PreFiber PP + PES?

They share the same construction (polypropylene depth media + PES membrane) and filtration area. The PreFiber A PP + PES states absolute ratings from 0.1 to 1.2 µm, with the prefilter pore size for each, and adds beverage applications; the PreFiber PP + PES is specified with nominal pore sizes from 0.1 to 0.65 µm.

PreFiber line