Prefiltration

PreFiber Max GF + PES

Glass microfiber + PES membrane cartridge

Clarification of high particle and colloid loads to protect final membranes

Two-layer cartridge: high-density glass microfiber prefilter and an asymmetric 0.1 to 0.6 µm PES membrane. Protects the sterilizing filter from high loads.

Line: PreFiber · Depth medium (polypropylene or glass microfiber) + PES membrane
Ratings: 0.1 µm to 0.6 µm
Lengths: 10″ · 20″ · 30″ · 40″
Manufacturing: Argentina · ISO 7 cleanroom

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PreFiber Max GF + PES, glass microfiber + PES membrane cartridge by Exova

Description

The PreFiber Max GF + PES combines a high-density glass microfiber prefilter and an asymmetric polyethersulfone (PES) final membrane in a single cartridge. It is designed to maximize the protection of final membranes when the fluid carries heavy particle and colloid loads.

The dense prefilter retains suspended solids, aggregated proteins, and colloids in depth and reduces the load reaching the sterilizing filter, extending the final filter's service life and lowering the total cost of operation. The asymmetric PES membrane provides high flow and microbial stability, and the pressure drop remains stable even in extended processes.

It is used in pharmaceuticals and biotechnology—clarification before sterilizing filtration, media and buffers, biological and protein solutions, parenterals, sera, and vaccines—and in wine, beer, cider, and juices. It is compatible with SIP, CIP, autoclave, and irradiation, and is manufactured in an ISO 7 cleanroom.

High-density glass prefilter

Retains suspended solids, aggregated proteins, and colloids before they reach the final membrane.

Asymmetric PES membrane

Polyethersulfone final filter with high flow and microbial stability.

Two-layer structure

Optimized for high depth-loading capacity, with 4,500 cm² of area per 10″.

Stable pressure drop

The pressure drop remains stable even in extended processes.

SIP, CIP, autoclave, and irradiation

Steam at 121 °C in-line or in an autoclave; hot water at 80 °C; peracetic acid and sodium hydroxide up to 1 %.

Manufactured in an ISO 7 cleanroom

Materials compliant with FDA 21 CFR 177 for food contact and non-toxic components according to the Argentine Food Code.

Technical specifications

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Materials

Upstream filter medium	High-density glass microfiber
Downstream filter medium (final filter)	Asymmetric polyethersulfone (PES) membrane
Outer and inner support layers	Polypropylene
Outer cage, core, and flat ends	Polypropylene
Fin	Polypropylene
Adapter (222 and 226)	Polypropylene with internal reinforcement
O-rings	Silicone, Viton®, Buna, EPDM, Teflon®-encapsulated Viton®

Dimensions

Nominal filtration area	4,500 cm² per 10″
Nominal length	10″ (254 mm), 20″ (508 mm), 30″ (762 mm), and 40″ (1,016 mm)
Nominal diameter	2.75″ (70 mm)

Operating conditions

Maximum differential pressure	5.5 bar (80 psi) at 25 °C
Maximum differential pressure in reverse flow	0.69 bar (10 psi) at 25 °C
Recommended change-out differential pressure	2 bar

Sterilization and sanitization

Compatibility	SIP, CIP, autoclave, and irradiation
Steam sterilization	Multiple cycles of 30 to 60 minutes at 121 °C, in-line or in an autoclave (1)
Hot water sanitization	Multiple cycles of 30 to 60 minutes at 80 °C (1)
Chemical sanitization	Multiple cycles of 30 to 60 minutes with peracetic acid up to 1 % (10,000 ppm), at room temperature
Chemical cleaning	Multiple cycles of 30 to 60 minutes with sodium hydroxide up to 1 % (10,000 ppm) (1)
Note (1)	Recommended only for single-open-end cartridges with internal reinforcement at the 226 / 222 O-ring fitting

Quality and compliance

Materials compliant with FDA 21 CFR 177 for food contact
Complies with European Commission Directive 2002/72/EC on plastic materials in contact with food, with its amendments up to 2008/39/EC
Non-toxic components according to the migration test of the Argentine Food Code and Mercosur SGT3 standards
Manufactured in an ISO 7 cleanroom

Applications

Clarification before sterilizing filtration
Media and buffer preparation
Biological and protein solutions
Parenterals, sera, and vaccines
Protection of final filtration systems
Clarification of wine, beer, cider, and juices
Prefiltration ahead of final membranes
Microbial stabilization

Industries

Pharmaceutical and biotech Food and beverage Wine industry SaniFlow filter housings

Frequently asked questions

What layers does the PreFiber Max GF + PES have?

Two filter media: high-density glass microfiber upstream and an asymmetric polyethersulfone (PES) membrane downstream. The support layers, cage, core, ends, and fin are polypropylene.

What pore sizes are available?

Nominal pore sizes of 0.1, 0.2, 0.4, and 0.6 µm, in lengths of 10″, 20″, 30″, and 40″, with a 2.75″ (70 mm) diameter.

How is it sterilized?

With in-line steam or in an autoclave at 121 °C, in multiple cycles of 30 to 60 minutes. This is recommended for single-open-end cartridges with internal reinforcement at the 226 or 222 O-ring fitting. It is compatible with SIP, CIP, autoclave, and irradiation.

At what differential pressure should it be changed out?

The recommended change-out differential pressure is 2 bar. The maximum allowed is 5.5 bar (80 psi) at 25 °C in normal flow and 0.69 bar (10 psi) at 25 °C in reverse flow.

What sets it apart from the PreFiber GF + PES?

Both combine glass microfiber and an asymmetric PES membrane. The PreFiber Max GF + PES uses a high-density glass prefilter, for heavy particle and colloid loads, with 4,500 cm² per 10″; the PreFiber GF + PES uses high-capacity glass, with 6,700 cm² per 10″.

PreFiber line